Agenda

Symposium
May 25, 2004
8:30-9:00         Registration
9:00-9:10         Opening Remarks

PART I  Rare Diseases and Trinucleotide Repeat Expansion Disorders
9:10-10:00      Spinocerebellar ataxia type 8: molecular genetics of an RNA expansion disorder
		Prof. Laura Ranum
		Department of Genetics, Cell Biology, and Development, 
		University of Minnesota, U.S.A.

10:00-10:50    Molecular mechanisms of neurodegeneration in polyglutamine diseases
		Prof. Shoji Tsuji
		Department of Neurology, Tokyo University, Japan 

10:50-11:10    Coffee Break

11:10-11:40     HSP27 and BCL-2 in Spinocerebellar Ataxia Type 3
		Prof. Mingli Hsieh (謝明麗)
		Department of Biology, Tunghai University

11:40-12:10     Genetic analysis in spinocerebellar ataxia in Taiwan: expansions of trinucleotide repeats in SCA8 and SCA17 are associated with different neurodegenerative diseases
		Prof. Chiung-Mei Chen (陳瓊美)
		Dept of Neurology, CGMH

12:10-2:00      Lunch Break and Discussion

2:00-2:50        Myotonic dystrophy type 2: RNA pathogenesis comes into focus
		Prof. Laura Ranum
		Department of Genetics, Cell Biology, and Development, 
		University of Minnesota, U.S.A.

2:50-3:20         Possible pathogenic mechanism underlying SCA8
		Prof. Guey-Jen Lee-Chen (李桂楨)
		Department of Life Science, National Taiwan Normal University

3:20-3:50         Coffee Break

3:50-4:20         Molecular investigations of SCA12
		Prof. Kang Fang (方剛)
		Department of Life Science, National Taiwan Normal University 

4:20-4:50         TRODAT-1 SPECT imaging contributes to the features of various spinocerebellar ataxias
		Prof. Bob Lu (陸清松)
		Dept of Neurology, CGMH 

4:50-5:20         The involvement of dopaminergic systems in SCA2: a positron emission tomography study 
		Prof. Bing-wen Soong (宋秉文)
		Department of Neurology, Yang-Ming University School of Medicine

May 26, 2004

9:00-9:50        Spinocerebellar ataxia type 5 and other unidentified ataxia genes: what will we learn next?  
		Prof. Laura Ranum
		Department of Genetics, Cell Biology, and Development, 
		University of Minnesota, U.S.A.

9:50-10:40      Molecular genetic approaches to sporadic ataxias
		Prof. Shoji Tsuji
		Department of Neurology, Tokyo University, Japan

10:40-11:00    Coffee Break

11:00-11:30     Candidate gene screening for spinocerebellar ataxia type 22
		Prof. Ming-yi Chung (鍾明怡)
		Department of Medical Research and Education, 
		Taipei Veterans General Hospital

11:30-12:00    Anti-gliadin antibody in patient with sporadic cerebellar ataxias
		Dr. Chin-san Liu (劉青山)
		Vascular and Genomic Center, Chunghua Christina Hospital

12:10-2:00      Lunch Break and Discussion

PART II  Biotechnology

2:00-2:40         Specific drug targeting 
		Prof. Shui-Tein Chen (陳水田)
		Institute of Biological Chemistry, Academia Sinica

2:40-3:20         Incremental generation of summarized clustering hierarchy for protein family analysis 
		Prof. Chien-Yu Chen (陳倩瑜)
		Graduate School of Biotechnology and Bioinformatics, 
		Yuan-Ze University

3:20-3:50         Coffee Break

3:50-4:30         ProteMiner-SSM: a web server for efficient analysis of protein tertiary substructures
		Prof. Yen-Jen Oyang (歐陽彥正)
		Department of Computer Science and Information Engineering, National Taiwan University
　
May 27, 2004

9:00-9:40         Inferring biological networks from experimental results: quantative and qualitave aspects
		Prof. Chao-Ping Hsu (許昭萍)
		Institute of Chemistry, Academia Sinica

9:40-10:20       Role of autoantibodies in molecular pathogenesis of lupus
		Prof. Kuang-Hui Sun (孫光蕙)
		Institute of Biotechnology in Medicine, National Yang-Ming University

10:20-10:40     Coffee Break

10:40-11:20     Deregulation of the p53-MDM2-p14ARF pathway in lung cancer 
		Prof. Yi-Ching Wang (王憶卿)
		Department of Life Science, National Taiwan Normal University

11:20-11:30     Closing Remarks


　
Workshop

May 26, 2004
2:00-5:00
Title:       Disease gene discovery
Speaker:  Prof. Ueng-Cheng Yang (楊永正) 
Place:      Computer Room, Yang-Ming University

May 27, 2004
9:00-12:00
Title:       Proteomics technology in spinocerebellar ataxia
Speaker:  Hsiang-Wen Tseng (曾湘文)
Place:      R707, Institute of Biological Chemistry, Academia Sinica 

May 27, 2004
2:00-5:00
Title:       Behavioral studies of animal models
Speaker:  Prof. Kwok-tung Lu(呂國棟)
Place:      Department of Life Science, National Taiwan Normal University

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